In stock
Growth Hormone Peptides
CJC-1295 DAC
Long-Acting GHRH Analogue
>98% HPLCVial (Lyophilised)CAS 446262-90-4
incl. VAT£44.90
In stock, ships today
Growth Hormone Peptides
Hexarelin
Examorelin
£24.90incl. VAT
SKU HEXARELIN-VIAL
Order before 12:00 on a working day and it ships today
Batch CoA included. HPLC purity and mass spec identity for your exact lot.
UK warehouse. Royal Mail Tracked 24, signature on delivery, 1 to 3 working days.
Plain packaging. Tamper evident, nothing on the outside naming the contents.
Stored at −20°C and shipped under inert atmosphere where the compound needs it.
Compound data
Per batch CoAPurity>99%
CAS number140703-51-1
Molecular formulaC47H58N12O6
Molecular weight887.059 g·mol−1
SequenceHis-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2
Half life<60minutes
StorageAway from light
PresentationVial (Lyophilised)
Figures above are the release specification. The certificate shipped with your vial carries the measured values for that specific lot. Email [email protected] with an order number for the raw chromatogram.
01
About this compound
Hexarelin was put together in the early 1990s by Romano Deghenghi and the Mediolanum Farmaceutici group in Milan, with later development passing through Pharmacia Italy. It carries the International Nonproprietary Name Examorelin, which is the label most pharmacological reference databases file the molecule under, even though almost nobody uses that name in the lab. The compound is a six-residue peptide with the sequence His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2, and that small methyl group on the tryptophan at position 2 is the entire reason it exists as a separate molecule rather than a footnote to GHRP-6.
The methyl group that makes the molecule
If you strip the 2-methyl out of the tryptophan, what is left is essentially GHRP-6. The 2-methyl-Trp modification slows enzymatic clearance and tightens the fit at the ghrelin receptor (GHS-R1a), and in published rat pituitary work Examorelin came out roughly an order of magnitude more potent per microgram than the parent compound on acute GH release. That difference is the headline data point in nearly every comparison paper in the Deghenghi files.
The CD36 side door
Most ghrelin-family work treats GHS-R1a as the only address the molecule visits. Hexarelin is unusual because it also binds CD36, the fatty acid translocase expressed on cardiomyocytes and macrophages, and a chunk of the published research on this peptide is built around that off-target site. The cardioprotection signal in rat infarct and isolated heart models, including work by Berti and the Locatelli group in Milan, traces back to CD36 binding rather than to the pituitary axis. If you are pulling references for a cardiac protocol rather than a somatotroph one, that is where the relevant literature sits.
Acute response, chronic attenuation
One of the consistent observations in the older human and animal pharmacology files is that the GH response to repeated Hexarelin dosing flattens over weeks of continuous exposure, while the acute single-dose response stays sharp. That is a useful design point for any study that runs longer than a few days, and it is the reason the molecule found its diagnostic niche in GH provocation testing rather than as a long-run secretagogue tool.
Reference points for the order
- CAS 140703-51-1, free base molecular weight 887.04 g/mol
- Sequence His-D-2-Me-Trp-Ala-Trp-D-Phe-Lys-NH2 as the acetate salt
- GHS-R1a agonist, with documented CD36 binding as a secondary site
- Acute potency higher than GHRP-6; chronic GH response known to attenuate
The vial itself
Each unit is lyophilised Examorelin acetate. Synthesis comes through UK and EU peptide manufacturers we have held long-running supply relationships with, never relabelled bulk from open marketplaces. Every batch is released against HPLC for purity and mass spectrometry for identity, and the CoA carrying the lot number printed on your vial can be requested through live chat before or after the order. If a vial ever fails to match its CoA on independent testing, the order is refunded in full.
Getting it to the bench
Around nine in ten UK orders leave the warehouse and reach the customer inside 48 hours. Live chat is run by people in UK working hours who can pull batch paperwork while you are still on the line. For studies needing ten vials or more, contact support directly rather than stacking the cart at retail, and pricing is reworked from there.
Sold strictly for in vitro laboratory research. Not for human or veterinary use. UK 18+.
02
Common questions
Is it legal to buy Hexarelin in the UK?
Yes, Hexarelin can be bought and held in the UK as a research chemical, supplied strictly for laboratory and in-vitro use. It is not a licensed medicine and is not approved for human or veterinary use, so we sell it for research purposes only. Note that Hexarelin is on the WADA prohibited list, which rules it out of any sporting context.
How fast is UK delivery, and how is Hexarelin shipped?
Around 90% of UK orders go out within 48 hours, with most arriving next day on a tracked Royal Mail service. The lyophilised vial is a stable freeze-dried powder, so it ships at ambient temperature in protective packaging without needing cold chain. On arrival, store it away from light and refrigerate for longer holding. We dispatch from UK and EU stock.
What does the Certificate of Analysis actually prove?
The CoA reports batch identity and purity from two independent methods. HPLC (high-performance liquid chromatography) gives the purity figure, above 99% for this batch, by separating the target peptide from process impurities. Mass spectrometry confirms the molecular weight matches the expected 887.06 g/mol, verifying you have Hexarelin and not a mislabelled or degraded peptide. Both data sets are kept per lot.
What is Hexarelin and what does the research look at?
Hexarelin is a synthetic hexapeptide and a growth hormone secretagogue that acts as an agonist at the GHS-R1a (ghrelin) receptor. It was developed in the 1990s by the Italian group around Romano Deghenghi. Published in-vitro and animal research has looked at its effect on growth hormone release from the pituitary and at GHS-R signalling and cardiac tissue. All findings are preclinical; we make no claims about effects in humans.
What is the sequence, and why the 2-methyl-tryptophan modification?
The sequence is His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2, a six-residue peptide with a C-terminal amide. The position-2 residue is a 2-methyl-tryptophan in the D-configuration. In published structure-activity work this modification was used to raise metabolic stability and receptor potency relative to earlier GHRP-6-type peptides, which is part of why Hexarelin became a reference secretagogue in the literature.
How do I reconstitute and store the vial?
Reconstitute the lyophilised powder with bacteriostatic or sterile water added slowly down the vial wall, then swirl rather than shake until dissolved; researchers pick the volume to suit their assay concentration. Keep the sealed vial away from light and refrigerated before use. Once reconstituted, hold it refrigerated and use within a few weeks. The dry powder is the most stable form for longer storage.
Research use only. This compound is supplied for in vitro laboratory research. It is not a medicine, not a supplement, and is not licensed for human or veterinary use. Purchasers must be 18 or over and confirm research intent at checkout.
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incl. VAT£19.90