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Healing & Recovery
TB-500
Synthetic Thymosin Beta-4
£44.90incl. VAT
SKU n/a
Order before 12:00 on a working day and it ships today
Batch CoA included. HPLC purity and mass spec identity for your exact lot.
UK warehouse. Royal Mail Tracked 24, signature on delivery, 1 to 3 working days.
Plain packaging. Tamper evident, nothing on the outside naming the contents.
Stored at −20°C and shipped under inert atmosphere where the compound needs it.
Compound data
Per batch CoAPurity>97%
CAS number885340-08-9
Molecular formulaC38H68N10O14
Molecular weight889.018 g·mol−1
SequenceAc-Leu-Lys-Lys-Thr-Glu-Thr-Gln (Ac-LKKTETQ)
Half life<4hours
StorageAway from light
PresentationNasal Spray, Vial
Figures above are the release specification. The certificate shipped with your vial carries the measured values for that specific lot. Email [email protected] with an order number for the raw chromatogram.
01
About this compound
TB-500 sits in a strange spot in the peptide world. People say the name and assume they mean the full Thymosin Beta-4 protein, all 43 amino acids of it. They don’t. TB-500 is the short synthetic fragment that was isolated because it carries most of the actin-binding activity of the parent molecule, without needing to make the whole protein in a flask. That is the version we supply, and that is the version every CoA in this listing refers to.
The vial holds 5mg of lyophilised peptide, white powder, sealed under argon. Reconstitute with bacteriostatic water inside a class II cabinet and you have a working stock for in vitro models of fibroblast migration, endothelial tube formation, or anything else where actin sequestration is the question you are trying to answer.
What sits behind the label
- Purity: >98% by reversed-phase HPLC, confirmed by mass spectrometry on every batch
- Identity: the TB-500 active fragment, not the full 43-residue parent peptide
- Form: lyophilised powder, acetate salt
- Vial size: 5mg, single-use rubber-stopper vial
- Origin: synthesised in UK and EU facilities, never relabelled bulk from unverified Chinese suppliers
Why labs come back for it
The published research lineage on TB-500 is built around soft-tissue and cardiac repair models. Mouse infarct studies, equine tendon work, corneal epithelial assays. If your protocol cites any of that literature, batch consistency is not a nice-to-have. A peptide that runs clean one lot and contaminated the next will ruin a six-week experiment. Every shipment we send out has been HPLC-traced and MS-confirmed before it left the bench, and the CoA is in the box. If the spec doesn’t match the paperwork, you get a refund. Not a credit, a refund.
Ordering and turnaround
Roughly 90% of UK orders go out and arrive inside 48 hours. We ship from a UK warehouse, so there is no customs delay and no mystery Royal Mail tracking that stops updating in Belgium. If you need ten vials or more for a larger study, message the team through live chat during UK office hours and we will quote bulk pricing per lot. Real humans answer. No bots, no ticket queue.
A note on the naming confusion
Several competitor listings will tell you TB-500 has 43 amino acids. That number is the length of the full Thymosin Beta-4 molecule. The TB-500 fragment is shorter, and that distinction matters once you start comparing your assay results against the published literature. If you need the full-length parent peptide for a specific comparison, ask us and we will point you to the right product.
Sold strictly for in vitro laboratory research. Not for human or veterinary use. UK 18+.
02
Common questions
Is it legal to buy TB-500 in the UK?
Yes, TB-500 can be bought and held in the UK when it is supplied and used strictly as a research chemical for in-vitro or laboratory work. It is not a licensed medicine and is not approved for human or veterinary use, so it cannot be sold for consumption. Note also that it sits on the WADA Prohibited List, which matters for any sport-related research context.
How fast is UK delivery, and how is TB-500 shipped?
Orders dispatch within 48 hours from inside the UK, so most labs receive their vials on a tracked next-day service after dispatch. The lyophilised powder is stable at ambient temperature for short transit, so it ships in protective packaging without a cold chain. We recommend moving it to a freezer on arrival; see the storage answer below for specifics.
What does the Certificate of Analysis actually prove?
The CoA reports two separate things: identity and purity. Mass spectrometry confirms the molecule matches the Ac-LKKTETQ fragment at the expected mass near 889 g/mol, while HPLC measures how much of the sample is that target peptide versus other peaks, here above 97 percent. Each lot is tested on its own, so the figures apply to the exact vial you receive, not a generic batch average.
Is TB-500 the same as full-length Thymosin Beta-4?
No. TB-500 is the short acetylated actin-binding fragment Ac-LKKTETQ, residues 17 to 23 of the native protein, with a molecular weight around 889 g/mol. Full-length Thymosin Beta-4 is a 43-residue molecule near 4960 g/mol. The fragment was developed to reproduce parts of the parent molecule's actin-sequestering activity in a smaller, easier-to-synthesise peptide, which is why catalogues list it under the Tb4 name.
What does published research on TB-500 look at?
Preclinical research on Thymosin Beta-4 and its Ac-LKKTETQ fragment has examined actin regulation, cell migration into wound sites, angiogenesis and inflammation in in-vitro and animal models, with particular attention to corneal, cardiac and musculoskeletal tissue. There are no controlled human clinical trials, and nothing here describes a treatment. The compound is sold for laboratory investigation only.
How is TB-500 reconstituted and stored for research?
For lab handling, the lyophilised powder is typically reconstituted with bacteriostatic or sterile water added down the vial wall, then swirled gently rather than shaken to avoid foaming. Store the sealed powder frozen, ideally near minus 20 C and away from light. Once in solution it is kept refrigerated at 2 to 8 C and not refrozen. These are storage notes for sample integrity, not a usage protocol.
Research use only. This compound is supplied for in vitro laboratory research. It is not a medicine, not a supplement, and is not licensed for human or veterinary use. Purchasers must be 18 or over and confirm research intent at checkout.
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